cailynn johnson about 1 year ago
Small2_immune_checkpoint_targeted_small_molecule_drug_development

NKG2A Immune Checkpoint Natural killer group protein 2A (NKG2A) is a cell surface receptor and member of the NKG2 family that can form a heterodimer with CD94 on the cell surface, also known as KLRD1, another NK cell-expressed C-type lectin. The non-classical MHC class I molecule HLA-E is the major ligand of NKG2A-CD94. These inhibitory receptors interact with MHC I ligands on target cells, leading to complete inhibition of NK cell granule polarization and cytotoxic granule release prevention.

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alex jamess about 1 month ago

An independent art collective showcasing modern and experimental visual art forms, fostering community engagement in the creative process. La Fuori

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