Single-cell sequencing technologies such as 10X Genomics, BD Phrapsody, and Illumina Hiseq have emerged that allow us to profile the genome, transcriptome and epigenomics of individual cells, unravel the heterogeneity of cell genotype, phenotype, and function within a complex cell population. Currently, single-cell sequencing technologies have been applied in a wide of life science research, including in oncology, developmental biology, microbiology, neuroscience, botany, and other fields. As an expert in the field of single-cell sequencing and analysis, Creative Biolabs provides the best and most comprehensive single-cell sequencing and analysis services. Learn more: Single Cell DNA-seq

Creative Biolabs is a leading service provider that focuses on ribosomal proteomics research. Based on our advanced platforms and extensive experience, now we can provide the ribosomal protein expression service based on various expression systems.

Given that it affects the rest of the world in addition to countries in west and central Africa, monkeypox is a disease of worldwide public health significance. Close contact with respiratory secretions, skin sores on an infected person, or recently contaminated objects can cause human-to-human transmission. Health professionals, family members, and other close contacts of current patients are more at risk because droplet respiratory particles typically require extended face-to-face contact. Learn more: monkeypox test

γδ T cells are a population of innate-like T lymphocytes characterized by T-cell receptors (TCRs) composed of γ and δ chains. They are widely distributed in the peripheral blood (PB) and mucosal tissues. γδ T cells have been revealed to exert dual roles in tumor immunity. On the one hand, γδ T cells suppress tumor occurrence by multiple mechanisms, including cytotoxicity against infected or tumor cells, cytokine and chemokine production, antigen-presenting functions, and regulatory abilities. On the other hand, γδ T cells exert suppressive effects on antitumor responses. Learn more: gamma delta T cell markers

Electrophysiology techniques provide a wealth of information regarding the molecular mechanisms that underlie the function and modulation of ion channels. Creative Biolabs is a contract research organization with over 10 years of expertise in our area of neurological electrophysiology expertise. We combine expertise, world-class facilities, and cutting-edge instrumentation to support companies involved in the research and development of products for neurological diseases. Learn more: electrophysiology of neurons

Recombinant monoclonal antibody to PDCD1. Camrelizumab is a human monoclonal antibody that can be potentially used in the treatment of Breast Cancer, Lung Cancer.

Glycolipids are the carbohydrate-attached lipids which provide energy and also serve as markers for cellular recognition. They might become a new type of promising non-viral gene delivery systems because of their low cytotoxicity, structural diversity, controllable aqua- and lipo-solubility, appropriate density and distribution of positive charges, high transfer efficiency and potential targeting function. Learn more: glycoprotein and glycolipid

Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-Ad fiber knob antibody variable domain are respectively connected to the N terminus of the anti-CEA IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. Learn more: Ad fiber knob CEA scFv IgG

Creative Biolabs combines deep, industry-leading expertise with an innovative Macrophage Therapeutics Development Platform to provide high-quality human/murine macrophage isolation and culture services. These isolated macrophages can be examined in vitro for their roles in phagocytosis, cytokine and mediator production, and other biological functions. Learn more: macrophage culture

Many factors should be considered when the immunogen is designed, such as length, molecular weight, secondary structure, purity, hydrophobicity, amino acids. Based on the following four major criteria, Creative Biolabs provides a full range of Immunogen Design services for hybridoma development.

As one of the most competitive biotechnology companies in the world, Creative Biolabs has extensive expertise and experience in the drug delivery field. We are committed to providing custom liposomes-based drug delivery services with state-of-the-art platforms. Meanwhile, on the basis of timely communication and reporting, our staff will ensure high-efficiency service to meet the strict project schedule. Learn more: creative delivery services

The development of intestinal microflora and its effects on gastrointestinal health have been the focus of research in recent years. As a biotechnology company keeping pace with times, Creative Biolabs has invested numerous energy and efforts in the development of probiotics-based drug discovery. Learn more: bacteria christensenella

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Learn more: f2 antibody

Empowered by state-of-the-art technologies and advanced platforms in the field of antibody discovery and immunotherapy, Creative Biolabs offers world-leading chimeric antigen receptor macrophage (CAR-MA) services for solid tumor treatment with academic purposes. Learn more: chimeric antigen receptor macrophages

Composed of ribosomal RNA molecules and proteins, ribosomes are important tools for protein synthesis in cells. ribosome complex profiling provides information on all ribosomes active in the cell at a specific time point and helps determine which proteins are actively translated in the cell. In life activities, mRNA translation is a key link that represents the flow of genetic information as well as defines the proteome.

Cardiovascular disease (CVD) is a general term for conditions affecting the heart or blood vessels. It's usually associated with a build-up of fatty deposits inside the arteries, known as atherosclerosis, and an increased risk of blood clots. It can also be associated with damage to arteries in organs such as the brain, heart, kidneys, and eyes. The risk factors for CVD include high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, among others. It is one of the main causes of death and disability but it can often largely be prevented with a healthy lifestyle. Learn more: cardiovascular diagnostic development

First demonstrated by Shinya Yamanaka's lab in 2006, the induced pluripotent stem cells (iPSCs) can be generated from different adult somatic cell types by the introduction of four transcription factors (OCT4, SOX2, KLF4, and MYC). With the pluripotency similar to embryonic stem cells (ESCs), iPSCs have shown great potential in drug discovery, disease modeling, and regenerative medicine research. Read Full Article: qPCR Analysis for Pluripotency Markers for iPSC

With the approval of two CAR-T cell therapies in 2017, the CAR-T cell treatment has been a promising tool for the treatment of advanced hematologic malignancies. However, although a lot of CAR-T cell therapies are under preclinical evaluation, this approach has not been proved to be as successful in solid tumors. One of the limitations in solid tumors lies in the poor penetration of T cells into tumors. To address this need, talented scientists from Creative Biolabs turn to genetically engineered CAR-MA, also termed MOTO-CAR, aiming to improve the ability of CAR cells to attack solid tumors. Learn more: CAR-macrophage

At Creative Biolabs, we are well-aware of the challenges of biopharmaceuticals development and the opportunities for non-IgG therapeutic antibodies development. Our rich experience and expertise in pharmacokinetics/pharmacodynamics (PK/PD) evaluation and customized solutions will help you get the useful information you need about your therapeutic antibody. With the advent of novel technologies, considerable advances have been made at Creative Biolabs in terms of PK/PD evaluation. Learn more: IgE antibodies PK/PD Evaluation

Reporter phage assays are very sensitive as they only detect active and viable cells. Another advantage is that the robustness of the assay and the high specificity of the phage, eliminating the need for lengthy sample preparation or purification. There is a large body of literature focusing on the construction and evaluation of many different reporter phages, such as luciferase reporter phage (LRP), green fluorescent protein (GFP) reporter phage, LacZ reporter phage, Ice nucleation (inaW) reporter phage, CelB reporter phage, etc.